Recombinant Human EGFR protein (Myc Tag, His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
Myc Tag, His Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <1.0 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human EGFR protein Leu25 - Ser645 (Accession# P00533) with a Myc tag and a His tag at the C-terminus. |
| 基因ID | 1956 |
| 蛋白编号 | P00533 |
| 预测分子量 | 74.2 kDa |
| SDS-PAGE | |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Epidermal growth factor receptor (EGFR, also known as ErbB1/HER1) is a cell-surface receptor tyrosine kinase that belongs to the ErbB family of receptors composed of four closely related members: EGFR (ErbB1/HER1), ErbB2 (HER2), ErbB3 (HER3) and ErbB4 (HER4). Under normal physiological conditions, EGFR is expressed in nearly all cell types and tissues, with the exception of hematopoietic lineage cells, and those in bone marrow, spleen, soft tissues, adrenal gland and specific brain tissues, where the EGFR protein is undetectable.
参考文献:
1. Wee, Ping, and Zhixiang Wang. Cancers vol. 9,5 52. 2. Hintzen, Gabriele et al. Frontiers in oncology vol. 12 892212.