Recombinant Human CD209 protein (His Tag)
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human CD209 protein Gln59-Ala404 (Accession# Q9NNX6-1) with a His tag at the N-terminus. |
| 基因ID | 30835 |
| 蛋白编号 | Q9NNX6-1 |
| 预测分子量 | 40.5 kDa |
| SDS-PAGE | 39-45 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells.
参考文献:
1. T B Geijtenbeek.et al. (2000) Cell.100(5):587-97. 2. Ludovic Tailleux. et al.(2005) PLoS Med. 2(12):e381.
Publications
| Species | Title |
|---|---|
Adv Sci (Weinh) Engineered Dual-Function Antibody-Like Proteins to Combat SARS-CoV-2-Induced Immune Dysregulation and Inflammation |