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验证数据展示

  • FC experiment of MG-63 using 98141-1-RR (same clone as 98141-1-PBS)

    FC experiment of MG-63 using 98141-1-RR (same clone as 98141-1-PBS)

    1x10^6 MG-63 cells (left) or A-172 cells (right) were surface stained with 0.25 ug Anti-Human PDGFR alpha/CD140a Rabbit Recombinant Antibody (98141-1-RR, Clone: 241658H4) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98141-1-PBS in a different storage buffer formulation.

  • Sandwich ELISA standard curve of MP01256-4

    Sandwich ELISA standard curve of MP01256-4

    Sandwich ELISA standard curve of MP01256-4, Human PDGFR alpha/CD140a Recombinant Matched Antibody Pair - PBS only. 84383-7-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard RP00003. 98141-1-PBS was HRP conjugated as the detection antibody. Range: 39.1-2500 pg/mL.

  • Sample test of MP01256-4

    Sample test of MP01256-4

    The mean PDGFR alpha/CD140a concentration was determined to be 2.6 ng/mL in SH-SY5Y cell extract based on a 1.0 mg/mL extract load and 7.0 ng/mL in human placenta tissue extract based on a 1.7 mg/mL extract load.

  • Sample test of MP01256-4

    Sample test of MP01256-4

    Serum of six individual healthy human donors was measured. The PDGFR alpha/CD140a concentration of detected samples was determined to be 2,557.7 pg/mL with a range of 1,472.3-4,545.6 pg/mL.

  • Cytometric bead array standard curve of MP01256-1

    Cytometric bead array standard curve of MP01256-1

    Cytometric bead array standard curve of MP01256-1, PDGFR alpha/CD140a Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84383-5-PBS. Detection antibody: 98141-1-PBS. Standard: RP00003. Range: 0.781-100 ng/mL.

  • Affinity and Kinetic Characterization of 98141-1-RR

    Affinity and Kinetic Characterization of 98141-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98141-1-RR against Human PDGFR alpha/CD140a were performed. The affinity constant is 2.26 nM.

Anti-Human PDGFR alpha/CD140a Rabbit Recombinant Antibody, PBS Only (Detector)

PDGFR alpha/CD140a Uni-rAbTM Recombinant Antibody for FC, Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test
Cat No. 98141-1-PBS

产品说明书

CloneNo. 241658H4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC, Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test

别名

PDGFRA, 241658H4, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98141-1-PBS targets PDGFR alpha/CD140a as part of a matched antibody pair:

MP01256-1: 84383-5-PBS capture and 98141-1-PBS detection (validated in Cytometric bead array)

MP01256-4: 84383-7-PBS capture and 98141-1-PBS detection (validated in Sandwich ELISA)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 FC, Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 platelet-derived growth factor receptor, alpha polypeptide
别名 PDGFRA, 241658H4, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A
计算分子量 123 kDa
GenBank蛋白编号BC015186
基因名称 PDGFR alpha
Gene ID (NCBI) 5156
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP16234
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Platelet-derived growth factor receptor alpha (PDGFR alpha, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival, and chemotaxis. Mutations in the PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.