验证数据展示
经过测试的应用
| Positive WB detected in | mouse ovary tissue, K-562 cells, rat ovary tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
19672-1-AP targets FOXL2-Specific in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse, rat, pig, chicken |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | forkhead box L2 |
| 别名 | FOXL2, BPES, BPES1, PFRK, PINTO |
| 计算分子量 | 39 kDa |
| 观测分子量 | 49 kDa |
| GenBank蛋白编号 | NM_023067 |
| 基因名称 | FOXL2 |
| Gene ID (NCBI) | 668 |
| RRID | AB_2878594 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P58012 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
FOXL2 is probable a transcriptional regulator. It is required to maintain the female phenotype throughout adulthood, and may provide clues to female infertility. Defects in FOXL2 are a cause of blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES) Defects in FOXL2 are a cause of premature ovarian failure type 3 (POF3). This antibody is specific to the C-term of FOXL2.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for FOXL2-Specific antibody 19672-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Adv Res Core fucosylation regulates the ovarian response via FSH receptor during follicular development | ||
J Adv Res Lactational high weight loss impairs follicular development by causing mitochondrial dysfunction of ovarian cells in sows and mitigated by butyrate supplement | ||
Cell Death Dis PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation | ||
Clin Cancer Res HMGA2-FOXL2 Axis Regulates Metastases and Epithelial-to-mesenchymal Transition of Chemo-resistant Gastric Cancer.
| ||
J Hazard Mater SO2 derivatives impair ovarian function by inhibiting Serpine1/NF-κB pathway-mediated ovarian granulosa cell survival | ||
Environ Int Tracing the epigenetic trajectory of EDC toxicity: Maternal BPAF drives uterine injuries via DNA methylation reprogramming. |
