×
Use Able AI chat for product recommendations

验证数据展示

  • FC experiment of NIH/3T3 using 98153-1-RR (same clone as 98153-1-PBS)

    FC experiment of NIH/3T3 using 98153-1-RR (same clone as 98153-1-PBS)

    1x10^6 NIH/3T3 cells were surface stained with 0.25 ug Anti-Mouse HER2/ErbB2 Rabbit Recombinant Antibody (98153-1-RR, Clone: 241366E6) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98153-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98153-1-RR

    Affinity and Kinetic Characterization of 98153-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98153-1-RR against Mouse HER2/ErbB2 were performed. The affinity constant is 1.50 nM.

Anti-Mouse HER2/ErbB2 Rabbit Recombinant Antibody, PBS Only

HER2/ErbB2 Uni-rAb® Recombinant Antibody for FC
Cat No. 98153-1-PBS

产品说明书

CloneNo. 241366E6

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

241366E6, CD340, EC:2.7.10.1, Erbb2, Her2

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

98153-1-PBS targets HER2/ErbB2 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原

CatNo: Eg0803

Product name: Recombinant Mouse Her2/ErbB2 protein (His Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-6*HIS

Domain: 23-653 aa of NM_001003817.1

Sequence: TQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPANASLSFLQDIQEVQGYMLIAHNRVKHVPLQRLRIVRGTQLFEDKYALAVLDNRDPLDNVTTAAPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVLRKNNQLAPVDMDTNRSRACPPCAPTCKDNHCWGESPEDCQILTGTICTSGCARCKGRLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALITYNTDTFESMLNPEGRYTFGASCVTTCPYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCAGVCYGLGMEHLRGARAITSDNIQEFAGCKKIFGSLAFLPESFDGNPSSGVAPLKPEHLQVFETLEEITGYLYISAWPESFQDLSVFQNLRVIRGRILHDGAYSLTLQGLGIHSLGLRSLRELGSGLALIHRNTHLCFVNTVPWDQLFRNPHQALLHSGNRPEEACGLEGLVCNSLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVWKGLPREYVRGKHCLPCHPECQPQNSSETCYGSEADQCEACAHYKDSSSCVARCPSGVKPDLSYMPIWKYPDEEGICQPCPINCTHSCVDLDERGCPAEQRASPVT

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
别名 241366E6, CD340, EC:2.7.10.1, Erbb2, Her2
计算分子量139 kDa
GenBank蛋白编号NM_001003817.1
基因名称 Erbb2
Gene ID (NCBI) 13866
RRIDAB_3672296
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP70424
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HER2, also known as ErbB2, Neu, and CD340, is a 185-kDa transmembrane glycoprotein member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. It has no ligand-binding domain and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.

||
New chat

Able™

正在加载，请稍候...