验证数据展示
产品信息
65670-1-PBS targets CD11a in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC Application Description |
| 经测试反应性 | mouse |
| 免疫原 |
N/A 种属同源性预测 |
| 宿主/亚型 | Rat / IgG2a |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | integrin alpha L |
| 别名 | Itgal, integrin alpha L, LFA 1 |
| GenBank蛋白编号 | BC145802 |
| 基因名称 | CD11a |
| Gene ID (NCBI) | 16408 |
| RRID | AB_3743288 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | B7ZN92 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).
