• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of K-562 using 67592-1-Ig (same clone as 67592-1-PBS)

    WB analysis of K-562 using 67592-1-Ig (same clone as 67592-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

TERF1 Monoclonal antibody, PBS Only

TERF1 Monoclonal Antibody for Indirect ELISA, WB
Cat No. 67592-1-PBS

产品说明书

CloneNo. 1D10G4

宿主/亚型

Mouse / IgG1

种属反应性

rat, mouse, human

应用

Indirect ELISA, WB

别名

Telomeric repeat-binding factor 1, t TRF1, PIN2, NIMA-interacting protein 2, hTRF1 AS

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

67592-1-PBS targets TERF1 in Indirect ELISA, WB applications and shows reactivity with rat, mouse, human samples.

经测试应用 Indirect ELISA, WB Application Description
经测试反应性 rat, mouse, human
免疫原

CatNo: Ag12540

Product name: Recombinant human TERF1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 118-419 aa of BC029378

Sequence: CQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKRSHKNLFLSKLQHGTQQQDLNKKERRVGTPQSTKKKKESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 telomeric repeat binding factor (NIMA-interacting) 1
别名 Telomeric repeat-binding factor 1, t TRF1, PIN2, NIMA-interacting protein 2, hTRF1 AS
计算分子量 439 aa, 50 kDa
观测分子量 48-50 kDa
GenBank蛋白编号BC029378
基因名称 TERF1
Gene ID (NCBI) 7013
RRIDAB_2918494
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDP54274
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Telomeres are nucleoprotein complexes located at chromosome ends that consist of tandem arrays of TTAGGG repeats bound to specific proteins. Telomeres protect chromosome ends from degradation and end-to-end fusions, prevent activation of DNA damage checkpoints, and modulate the maintenance of telomeric DNA by telomerase. TERF1 (telomeric repeat-binding factor 1) binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. It's one component of the shelterin complex, which involved in the regulation of telomere length and protection.