验证数据展示
产品信息
17876-1-PBS targets SLC6A18 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag11685 Product name: Recombinant human SLC6A18 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 224-413 aa of BC056757 Sequence: LIRGLTLPGATKGLIYLFTPNMHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMTSLYASIAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLNATWPKRVAQLPLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGMLFTL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | solute carrier family 6, member 18 |
| 别名 | |
| 计算分子量 | 628 aa, 71 kDa |
| 观测分子量 | ~70 kDa |
| GenBank蛋白编号 | BC056757 |
| 基因名称 | SLC6A18 |
| Gene ID (NCBI) | 348932 |
| RRID | AB_3085543 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q96N87 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SLC6A18, also known as XTRP2 and B0AT3, belongs to the SLC6 family of proteins. SLC6A18 acts as specific transporters for neurotransmitters, amino acids and osmolytes such as betaine, taurine and creatine. SLC6A18 is highly expressed at the luminal membrane of kidney proximal tubules and displays 50% identity with SLC6A19 (B0AT1), which is the main neutral amino acid transporter in both kidney and small intestine (PMID: 19478081, PMID: 21420947).
