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Recombinant Rat TrkA protein (rFc Tag) (HPLC verified)

种属

Rat

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg3210

Print datasheet

Synonyms

High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, Ntrk1, p140-TrkA, Slow nerve growth factor receptor

验证数据展示

  • Purity of Recombinant Rat TrkA was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Rat TrkA was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Rat TrkA was greater than 90% as determined by SEC-HPLC.

    The purity of Rat TrkA was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Rat TrkA protein Ala33-Pro418 (Accession# P35739-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 59109
蛋白编号 P35739-1
预测分子量 68.5 kDa
SDS-PAGE 80-120 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

TrkA belongs to the Trk receptor family, which plays a central role in a very broad range of cellular responses and is implicated in a spectrum of human pathologies, including Alzheimer’s, Parkinson’s diseases, pain, and notably cancer. TrkA in particular was first to be identified as a specific receptor for NGF and is activated upon NGF binding.

参考文献:

1. Zhao S, et al. (2020). Commun Biol. 3(1):706.
2. Kaplan DR, et al. (1991). Nature. 350:158–160.
3. Klein R, et al. (1991). Cell. 65:189–197.
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