Recombinant Rat CX3CL1 protein (rFc Tag)(HPLC verified)
种属
Rat
纯度
>90 %, SDS-PAGE
>90 %, SEC-HPLC
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Rat CX3CL1 protein Thr30-Arg335 (Accession# O55145) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 89808 |
| 蛋白编号 | O55145 |
| 预测分子量 | 58.8 kDa |
| SDS-PAGE | 70-100 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes—mainly NK cells, T cells and dendritic cells. CX3CL1 has a cysteine signature motif -Cys-X-X-X-Cys- at the N-terminal end and is the only known representative of the δ-chemokine family. CX3CL1 shows high expression in the brain, where it is synthesized by neurons and has neuroprotective functions. High expression of CX3CL1 is also found in the kidneys, lungs, bones and blood vessels.
参考文献:
1. Liu W, et al. (2016). Arch Immunol Ther Exp.Oct;64(5):371-83. 2. Korbecki J, et al. (2020). Int J Mol Sci. May 25;21(10):3723. 3. Conroy M.J., et al. (2020). Adv Exp Med Biol. 1231:1-12.

