Recombinant Rat CX3CL1 protein (rFc Tag)(HPLC verified)

种属

Rat

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg3280

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Synonyms

Acc1, CX3C membrane-anchored chemokine, C-X3-C motif chemokine 1, Fkn, Fractalkine



产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Rat CX3CL1 protein Thr30-Arg335 (Accession# O55145) with a rabbit IgG Fc tag at the C-terminus.
基因ID 89808
蛋白编号 O55145
预测分子量 58.8 kDa
SDS-PAGE 70-100 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes—mainly NK cells, T cells and dendritic cells. CX3CL1 has a cysteine signature motif -Cys-X-X-X-Cys- at the N-terminal end and is the only known representative of the δ-chemokine family. CX3CL1 shows high expression in the brain, where it is synthesized by neurons and has neuroprotective functions. High expression of CX3CL1 is also found in the kidneys, lungs, bones and blood vessels.

参考文献:

1. Liu W, et al. (2016). Arch Immunol Ther Exp.Oct;64(5):371-83. 2. Korbecki J, et al. (2020). Int J Mol Sci. May 25;21(10):3723. 3. Conroy M.J., et al. (2020). Adv Exp Med Biol. 1231:1-12.

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