Recombinant Rat CD68 protein (rFc Tag) (HPLC verified)
种属
Rat
纯度
>90 %, SDS-PAGE
>90 %, SEC-HPLC
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Rat CD68 protein Lys20-Ser295 (Accession# Q4FZY1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 287435 |
| 蛋白编号 | Q4FZY1 |
| 预测分子量 | 55.8 kDa |
| SDS-PAGE | 70-125 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD68, also known as GP110, LAMP4, or SCARD1, is widely expressed in monocyte cell types, such as macrophages, microglia, and osteoclasts. CD68 belongs to the lysosome-associated membrane protein (LAMP) family and is involved in various cellular processes such as autophagy, lipid transport, and aging. Additionally, CD68 is also a member of the scavenger receptor family and plays a critical role in promoting phagocytosis, which is essential for the clearance of cellular debris, pathogens, and the maintenance of tissue homeostasis. CD68 is also a pan-macrophage marker and is the most commonly used universal marker for the identification and quantification of tumor-associated macrophages (TAMs) .
参考文献:
1. Zhang J, et al. (2022). Sci Rep. 12(1):7844. 2. Wilke S, et al. (2012). BMC Biol. 10:62. 3. Song J, et al. (2023). Pathol Res Pract. 249:154739.
