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Recombinant Mouse MST1R protein (rFc Tag) (HPLC verified)

种属

Mouse

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg2647

Print datasheet

Synonyms

CD136, EC:2.7.10.1, Macrophage-stimulating protein receptor, Macrophage-stimulating protein receptor alpha chain, Macrophage-stimulating protein receptor beta chain

验证数据展示

  • Purity of Recombinant Mouse MST1R was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse MST1R was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Mouse MST1R was greater than 90% as determined by SEC-HPLC.

    The purity of Mouse MST1R was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 CHO-derived Mouse MST1R protein Thr25-Arg960 (Accession# Q62190-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 19882
蛋白编号 Q62190-1
预测分子量 127.2 kDa
SDS-PAGE 28-32 kDa, 90-120 kDa and 200-220 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Mst1r (macrophage-stimulating 1 receptor), encodes a cell surface receptor for macrophage-stimulating 1 (MST1, also known as MSP) with tyrosine kinase activity. Mst1r is critical for innate immunity and plays an important role for host defense against viral infection. The upregulation of MST1R tyrosine kinase expression is a molecular event of particular interest in many epithelial neoplasms, as it can mediate oncogenic phenotypes and addiction to KRAS signaling.

参考文献:

1. Dai W, et al. (2016). Proc Natl Acad Sci U S A. Mar 22;113(12):3317-22.
2. Babicky, M. L., et al. (2019). Oncogene. Jul;38(28):5599-5611.
3. Wang W, et al. (2024). Cell Biosci. Aug 29;14(1):109.
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