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Recombinant Mouse CD107b/LAMP2 protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2029

Print datasheet

Synonyms

CD107b, Lamp2, Lamp 2, Mac3

验证数据展示

  • Purity of Recombinant Mouse CD107b was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse CD107b was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Mouse CD107b protein Leu26-Asn379 (Accession# P17047-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 16784
蛋白编号 P17047-1
预测分子量 65.5 kDa
SDS-PAGE 85-120 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

LAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis. Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells. LAMP2 is involved in lysosomal stability and autophagy. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may play a role in tumor cell metastasis.

参考文献:

1. R Kundra, S Kornfeld. (1999) J Biol Chem. Oct 22;274(43):31039-46.
2. Eeva-Liisa Eskelinen, et al. (2002) Mol Biol Cell. Sep;13(9):3355-68.
3. V Sarafian, et al. (1998) Int J Cancer. Jan 5;75(1):105-11.