Recombinant Mouse IL-20RB protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse IL-20RB protein Val27-Ser225 (Accession# E9Q9A6) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 213208 |
| 蛋白编号 | E9Q9A6 |
| 预测分子量 | 48.3 kDa |
| SDS-PAGE | 50-65 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Interleukin-20 receptor subunit beta (IL-20RB) is a component of the interleukin-20 receptor (IL-20R) complex. This receptor complex plays a significant role in immune regulation, tissue homeostasis, host defense, and oncogenesis. The interaction with these cytokines leads to the activation of the JAK/STAT signaling pathway, influencing various immune responses. IL-20RB has been implicated in various diseases, particularly in the context of autoimmune diseases and cancer.
参考文献:
1.Chen J, et al. (2018). J Leukoc Biol. 104(5):953-959. 2.He Y, et al. (2022). J Clin Invest. 132(20):e157917. 3.Li XH, et al. (2023). J Transl Med. 21(1):911.
