Recombinant Mouse IL-20 protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse IL-20 protein Leu25-Leu176 (Accession# Q9JKV9) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 58181 |
| 蛋白编号 | Q9JKV9 |
| 预测分子量 | 43.6 kDa |
| SDS-PAGE | 39-48 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
As a member of the IL-10 family, IL-20 functions as a proinflammatory cytokine by binding to its complex receptors (IL-20R1/IL-20R2 and IL-20R2/IL-22R1) on target cells. Excessive IL-20 expression is associated with chronic inflammatory diseases, such as rheumatoid arthritis and osteoporosis.
参考文献:
1. Wang HH. et al. (2022). J Biomed Sci. 29(1):36. 2. Hsu YH. et al. (2011). J Exp Med. 208(9):1849–1861. 3. Hsu YH. et al. (2017). Drug Discov Today. 22(6):960–964.
