Recombinant Mouse IL-19 protein (rFc Tag)(HPLC verified)
种属
Mouse
纯度
>90 %, SDS-PAGE
>90 %, SEC-HPLC
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse IL-19 protein Leu25-Ala176 (Accession# Q8CJ70) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 329244 |
| 蛋白编号 | Q8CJ70 |
| 预测分子量 | 43.6 kDa |
| SDS-PAGE | 50-60 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
IL-19 is found within the IL-10 family gene cluster: IL-10, -19, -20, -22, -24 (MDA-7), -26 (AK155), -28, and -29. IL-19 derived primarily from macrophages and, to a lesser extent, from B cells and nonimmune cells including epithelial cells, endothelial cells, skin keratinocytes, and fetal membranes. Many reports showed that IL-19 has proinflammatory effects.
参考文献:
1. Wolk K, et al. (2002). Journal of Immunology. 168(11):5397-5402. 2. Menon R, et al. (2006). Journal of Maternal-Fetal and Neonatal Medicine. 19(4):209-214. 3. Chen YY, et al. (2013). Clin Dev Immunol. 2013:294320.

