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Recombinant Mouse IFNA9 protein (rFc Tag) (HPLC verified)

种属

Mouse

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg3040

Print datasheet

Synonyms

Ifa9, IFN-alpha 9, IFN-alpha-9, Interferon alpha-9

验证数据展示

  • Purity of Recombinant Mouse IFNA9 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse IFNA9 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Mouse IFNA9 was greater than 90% as determined by SEC-HPLC.

    The purity of Mouse IFNA9 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Mouse IFNA9 protein Cys24-Glu190 (Accession# P09235) with a rabbit IgG Fc tag at the C-terminus.
基因ID 15972
蛋白编号 P09235
预测分子量 45.1 kDa
SDS-PAGE 44-52 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Interferons (IFNs) are a family of cytokines with potent antiviral, antiproliferative, and immunomodulatory properties. Ifna9 is a type I interferon that binds to the interferon alpha receptor (IFNAR), which consists of two subunits: IFNAR1 (alpha-subunit) and IFNAR2 (beta-subunit). Ifna9 is expressed in various tissues and is induced in L929 cells 6-9 hours after Poly(I).Poly(C) treatment. Differential expression of the IFN-alpha subtypes is observed in influenza A/NWS/33- and B/Lee/40-infected L929 cells. Ifna9 interacts with several proteins, including Ifnar1, Ifna14, Ifna5, Ifna12, Ifna11, Jak2, Irf7, Irf3, and Egfr. These interactions are crucial for the signaling pathways involved in the immune response and antiviral activities. The human ortholog of Ifna9 is IFNA1.

参考文献:

1. Bartlett EJ, et al. (2004). Immunol Cell Biol. 82(2):119-26.
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