Recombinant Mouse IFN-alpha-7/IFNA7 protein (mFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
mFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse IFN-alpha-7 protein Cys24-Glu190 (Accession# P06799) with a mouse IgG Fc tag at the C-terminus. |
| 基因ID | 15970 |
| 蛋白编号 | P06799 |
| 预测分子量 | 45.7 kDa |
| SDS-PAGE | 47-55 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
The interferon (IFN) family constitutes an important class of cytokines and is composed of transcriptionally activated and secreted proteins with pleiotropic biological effects on the host. IFNs play a central role in the resistance of mammalian hosts to pathogens, and in the modulation of antiviral and immune responses.The IFN proteins group into two classes: type I (IFN-alpha and-beta) and type II (IFN-gamma), which bind two distinct cell surface receptors, type I and type II IFN receptors, respectively. IFN-alpha-7 belongs to the type I interferon family and produced by macrophages. IFN-alpha-7 have antiviral activities.
参考文献:
1.Solis M. et al. (2006). Biochem Pharmacol. 72(11):1469-1476.
