验证数据展示
产品信息
| Product name | Mouse IL-10 Antibody Pair Set |
| Tests | 10×96 well plate |
| Assay type | Sandwich |
| Range | 62.5-4000 pg/mL |
| Reactivity | Mouse |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 16153 |
| Specificity | Please see the product datasheet |
| Entrez Gene ID | 16153(P18893) |
| Alternate Names | CSIF, Il 10, Il10, interleukin 10 |
背景信息
Interleukin (IL)-10 is an anti-inflammatory cytokine, produced by T helper (Th) cells, macrophages, monocytes, and B cells, that plays a crucial role in preventing inflammatory and autoimmune pathologies. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway. IL-10, along with its receptors, describes an important role in pathogenesis of various diseases, including infectious, inflammatory, autoimmune diseases. IL-10 mutations are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
产品特性
- Optimization: The use of matched antibody pairs that have undergone rigorous screening and validation can significantly reduce the time required for development.
- Flexible Packaging: The availability of multiple specifications allows for the detection needs of various sample quantities to be met.
- Economic: This product offers cost-effective solutions for researchers who want to save on their budget while exploring unique sample detection systems in their assays.
- Natural Sample Testing: The product has undergone thorough testing using natural samples.
运输与储存
| Shipping | The product is shipped at 2-8℃. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20℃. Do not use past expiration date. |
