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Recombinant Mouse JAM-A/Junctional Adhesion Molecule A protein (rFc Tag) (HPLC verified)

种属

Mouse

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg3117

Print datasheet

Synonyms

CD321, F11r, Jam1, JAM-1, JAM-A

验证数据展示

  • Purity of Recombinant Mouse JAM-A was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse JAM-A was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Mouse JAM-A was greater than 90% as determined by SEC-HPLC.

    The purity of Mouse JAM-A was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Mouse JAM-A protein Lys27-Gly238 (Accession# O88792) with a rabbit IgG Fc tag at the C-terminus.
基因ID 16456
蛋白编号 O88792
预测分子量 48.9 kDa
SDS-PAGE 50-52 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

F11 receptor (F11R), also called Junctional Adhesion Molecule-A (JAM-A), is a transmembrane protein that belongs to the immunoglobulin superfamily of cell adhesion molecules. F11R is present in epithelial cells, endothelial cells, leukocytes, and blood platelets. F11R participates in regulating various biological processes, as diverse as paracellular permeability, tight junction formation and maintenance, leukocyte transendothelial migration, epithelial-to-mesenchymal transition, angiogenesis, reovirus binding, and platelet activation.

参考文献:

1.Fang TJ. et al. (2016) Int J Rheum Dis. 19(2):127-133.
2.Czubak-Prowizor K. et al. (2022) Mol Cell Biochem. 477(1):79-98. 
3.Kamola P. et al. (2023) Platelets. 34(1):2214618.