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Recombinant Mouse ESM1 protein (rFc Tag)(HPLC verified)

种属

Mouse

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg2784

Print datasheet

Synonyms

Endothelial cell-specific molecule 1, ESM-1

验证数据展示

  • Purity of Recombinant Mouse ESM1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse ESM1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Mouse ESM1 was greater than 90% as determined by SEC-HPLC.

    The purity of Mouse ESM1 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Mouse ESM1 protein Ala22-Arg184 (Accession# Q9QYY7) with a rabbit IgG Fc tag at the C-terminus.
基因ID 71690
蛋白编号 Q9QYY7
预测分子量 43.8 kDa
SDS-PAGE 40-48 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Endothelial cell specific molecule 1 (ESM1), also known as endocan, is a secreted protein that is involved in endothelium-dependent pathological disorders. ESM1 is overexpressed in various tumors such as lung cancer, head and neck squamous cell carcinoma as well as ovarian cancer and overexpression of ESM1 is reported to induce tumor formation through regulating cell proliferation and facilitating tumor growth. ESM1 function is mainly associated with inflammatory response, angiogenesis and tumor cell growth.

参考文献:

1.Liu W, et al. (2024) Ann Transl Med. 20;12(5):104.
2.Li J, et al. (2022) Biomed Res Int. 2022:5328192.
3.Li YK, et al. (2023) Int J Biol Sci. 19(1):258-280.
4.Yang L, et al. (2023) Aging (Albany NY). 15(8):2920-2936.
5.Yang J, et al. (2023) Cancers (Basel). 16(1):194.
6.Zhang J, et al. (2024) Mol Cancer. 23(1):94.