Recombinant Mouse ENPEP protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse ENPEP protein Arg41-Pro945 (Accession# P16406) with a rabbit IgG Fc tag at the N-terminus. |
| 基因ID | 13809 |
| 蛋白编号 | P16406 |
| 预测分子量 | 131.0 kDa |
| SDS-PAGE | 120-150 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Glutamyl aminopeptidase, encoded by ENPEP, is a membrane protein, which can cut the N‐terminal aspartic acid of angiotensin II, used to increase blood pressure. In previous studies, ENPEP has been shown to contribute to the development of the immune system. ENPEP has also been associated with tumorigenesis in some cancers, such as breast cancer, leukemia, and renal cancer. ENPEP expression levels have been shown to be a prognostic factor in colorectal cancer, linked to the increased survival of patients.
参考文献:
1. Reaux A. et al. (2000). Biochem Soc Trans. 28(4):435-40. 2. Blanco L. et al. (2014). BMC Cancer. 14:386. 3. Haznedaroglu IC. et al. (2016). Eur Rev Med Pharmacol Sci. 20(19):4089-4111. 4. Yuan Y. et al. (2020). Front Oncol. 10:595.
