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Recombinant Mouse CX3CL1 protein (His Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg0704

Print datasheet

Synonyms

Cx3cl1, ABCD 3, CX3C, Cxc3, Scyd1

验证数据展示

  • Purity of Recombinant Mouse CX3CL1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse CX3CL1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Mouse CX3CL1 protein Gln25-Arg337 (Accession# O35188) with a His tag at the C-terminus.
基因ID 20312
蛋白编号 O35188
预测分子量 34 kDa
SDS-PAGE 60-85 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CX3CL1, also known as fractalkine, is a trans-membrane chemokine that acts as a ligand for both CX3CR1 and integrins αvβ3 and α4β1. CX3CL1 is expressed by many hematopoietic and nonhematopoietic cells, including macrophages, endothelial cells, neurons, and fibroblasts. It is involved in immune responses and inflammation. CX3CL1 exists in a membrane-anchored molecule and a soluble form, generated by proteolytic cleavage.

参考文献:

1. D L Rossi, et al. (1998) Genomics. 47(2):163-70.
2. K J Garton, et al. (2001) J Biol Chem. 276(41):37993-8001. 
3. Christian Hundhausen, et al. (2003) Blood. 102(4):1186-95.
4. Brian A Jones, et al. (2010) Mol Interv. 10(5):263-70. 
5. Masaaki Fujita, et al. (2012) J Immunol. 189(12):5809-19.