Recombinant Mouse CRTAM/CD355 protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse CRTAM protein Ala17-Ala284 (Accession# Q149L7-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 54698 |
| 蛋白编号 | Q149L7-1 |
| 预测分子量 | 55.5 kDa |
| SDS-PAGE | 65-85 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Cytotoxic and regulatory T cell molecule (CRTAM, also known as CD355) is an immunoglobulin-superfamily transmembrane protein with V and C1-like Ig domains, which is involved in epithelial cell adhesion. CRTAM is critical to instruct the differentiation of CD4+ cytotoxic T cells (CTL) through the induction of eomesodermin and CTL-related genes. It also regulates CD8+ T cell retention within the lymph node and eventually effector function.
参考文献:
1.Yeh JH, et al. (2008) Cell. 7;132(5):846-59. 2.Garay E, et al. (2010) J Cell Biochem. 1;111(1):111-22. 3.Takeuchi A, et al. (2015) J Exp Med. 11;213(1):123-38. 4.Takeuchi A,et al. (2009) J Immunol. 1;183(7):4220-8.
