Recombinant Mouse CACHD1 protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse CACHD1 protein Asp52-Pro1109 (Accession# Q6PDJ1-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 320508 |
| 蛋白编号 | Q6PDJ1-1 |
| 预测分子量 | 144.1 kDa |
| SDS-PAGE | 140-150 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CACHD1, or cache domain containing 1, is highly expressed in the mammalian central nervous system (CNS), with particular expression in the thalamus, hippocampus, and cerebellum.This protein is thought to be involved in the modulation of voltage-gated calcium channels, particularly the CaV3 (T-type) channels, which are important for regulating neuronal excitability. Cachd1 is also expressed in neuronal progenitors, functions downstream of asymmetric environmental signals, and influences timing of the normally asymmetric patterns of neurogenesis.
参考文献:
1. Cottrell GS. et al. (2018). J Neurosci. 38(43):9186-9201. 2. Powell GT. et al. (2024) . Science. 384(6695):573-579.
