Recombinant Mouse CXCL1 protein (hFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
hFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse CXCL1 protein Ala25-Lys96 (Accession# P12850) with a human IgG2 Fc tag at the C-terminus. |
| 基因ID | 14825 |
| 蛋白编号 | P12850 |
| 预测分子量 | 33.8 kDa |
| SDS-PAGE | 33-37 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CXCL1 a is a member of CXC family and also known as keratinocyte-derived chemokines (KC) or growth-related oncogene (GRO). CXCL1 is expressed by macrophages, neutrophils and epithelial cells. CXCL1 binding specifically to the CXC chemokine receptor CXCR2, is involved in fibrogenesis and angiogenesis. This protein also plays a role in inflammation and as a chemoattractant for neutrophils. CXCL1 is upregulated in some types of human cancer, including colorectal, bladder, breast, prostate and skin cancers.
参考文献:
1. D. Wang. et al. (2000). Oncogene. 19: 4647-4659. 2. Verbeke H. et al.(2011). Cytokine Growth Factor Rev. 22: 345-358. 3. Miyake M. et al.(2014). Pathol Res Pract. 210: 74-75. 4. Dhawan P. et al.(2002). J Leukoc Biol. 72: 9-18.
