Recombinant Mouse CD43 protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 |
Not tested |
来源 | HEK293-derived Mouse CD43 protein Asp20-Gly248 (Accession# P15702) with a rabbit IgG Fc tag at the C-terminus. |
基因ID | 20737 |
蛋白编号 | P15702 |
预测分子量 | 48.8 kDa |
SDS-PAGE | kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage.CD43 has also been suggested to be present in colon adenomas and colon carcinomas. CD43 also mediates leukocyte homing to inflammatory sites through binding to E-selectin expressed in endothelial cells from inflamed tissues.
参考文献:
1. Alisson-Silva F. et al. (2019) Sci Rep. 9(1):8628. 2. Batdorf BH. et al. (2017) Tumour Biol. 23(4):193-201. 3. Matsumoto M. et al. (2008) J Immunol. 181(5):3628-35.