• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Recombinant Mouse CD36 protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3464

Print datasheet

Synonyms

Glycoprotein IIIb, GPIIIB, GPIV, PAS IV, PAS-4

验证数据展示

  • Purity of Recombinant Mouse CD36 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse CD36 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Mouse CD36 protein Gly30-Lys439 (Accession# Q08857) with a rabbit IgG Fc tag at the C-terminus.
基因ID 12491
蛋白编号 Q08857
预测分子量 72.7 kDa
SDS-PAGE 85-120 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CD36 is also named as GP3B, GP4, Glycoprotein IIIb (GPIIIB), PAS-4 and Fatty acid translocase (FAT). CD36, also known as the scavenger receptor B2, is a multifunctional receptor widely expressed in various organs. CD36 is a vital molecule in lipid metabolism. In heart and muscle, CD36 is the main (long-chain) fatty acid transporter, regulating myocellular fatty acid uptake via its vesicle-mediated reversible trafficking (recycling) between intracellular membrane compartments and the cell surface. CD36 is subject to various types of post-translational modification. CD36 is expressed in various tissues, including endothelial cells, cardiac muscle cells, renal tubular epithelial cells, liver cells, adipocytes, platelets, and macrophages, and is involved in many pathophysiological processes, including immune regulation and metabolic regulation. CD36 mediates a mitochondrial metabolic switch from oxidative phosphorylation to superoxide production in response to its ligand, oxidized LDL.

参考文献:

1.Shu H, et al. (2022) Cardiovasc Res. 118(1):115-129.
2.Kim TT, Dyck JR. (2016) Biochim Biophys Acta. 1861(10):1450-60.
3.Luiken JJ, et al. (2016) Biochim Biophys Acta. 1862(12):2253-2258.
4.Campbell SE, et al. (2004) J Biol Chem. 279(35):36235-41.
5.Bezaire V, et al. (2006) Am J Physiol Endocrinol Metab. 290(3):E509-15.