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Recombinant Mouse CD229/SLAMF3 protein (His Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg1586

Print datasheet

Synonyms

CD229, Cell surface molecule Ly-9, Ly9, Ly-9, Lymphocyte antigen 9

验证数据展示

  • Purity of Recombinant Mouse CD229 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse CD229 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Mouse CD229 protein Lys48-Arg453 (Accession# Q01965) with a His tag at the C-terminus.
基因ID 17085
蛋白编号 Q01965
预测分子量 46.2 kDa
SDS-PAGE 60-70 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Signaling lymphocytic activation molecule 3 (SLAMF3), also known as CD229 or Ly9, is a type I transmembrane glycoprotein that belongs to the SLAM family receptors. It is composed of an extracellular region, which consists of four Ig-like domains, a transmembrane region, and a cytoplasmic tail, which includes two immunoreceptor tyrosine-based signaling motifs (ITSMs) and other tyrosine residues that act as binding sites for the SH2 structural domains. SLAMF3 is mainly expressed in immune cells, such as T, B, and natural killer cells, and it is involved in the fundamental activation and suppression of these immune cells, as well as the regulation of complex immune networks.

参考文献:

1.Tovar V, et al. (2000) Immunogenetics. 51(10):788-93.
2.Romero X, et al. (2005) J Immunol. 174(11):7033-42.
3.Sandrin MS, et al. (1996) Immunogenetics. 43(1-2):13-9.
4.de la Fuente MA, et al. (2001) Blood. 97(11):3513-20.
5.Zhou T, et al. (2024) Int Immunopharmacol. 133:112088.