Recombinant Mouse CCL12/MCP-5 protein (rFc Tag) (HPLC verified)

种属

Mouse

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg3315

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Synonyms

C-C motif chemokine 12, Ccl12, MCP-1-related chemokine, Mcp5, MCP-5



产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Mouse CCL12 protein Gly23-Gly104 (Accession# Q62401) with a rabbit IgG Fc tag at the C-terminus.
基因ID 20293
蛋白编号 Q62401
预测分子量 35.6 kDa
SDS-PAGE 37-47 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CCL12, also known as MCP-5, is a small cytokine belonging to the CC chemokine family. It is a structural and functional homologue of human MCP-1. CCL12 is found predominantly in lymph nodes and thymus under normal conditions, and its expression can be markedly induced in activated macrophages both in vitro and in vivo. CCL12 is involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.

参考文献:

1. M N Sarafi. et al. (1997) J Exp Med.185(1):99-109. 2. D.A. Luster. et al. (1998) J Exp Med. 338 (1998), 436-445. 3. G Q Jia. et al. (1996) J Exp Med. 184(5):1939-51.

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