Recombinant Mouse CCL12/MCP-5 protein (rFc Tag) (HPLC verified)
种属
Mouse
纯度
>90 %, SDS-PAGE
>90 %, SEC-HPLC
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse CCL12 protein Gly23-Gly104 (Accession# Q62401) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 20293 |
| 蛋白编号 | Q62401 |
| 预测分子量 | 35.6 kDa |
| SDS-PAGE | 37-47 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CCL12, also known as MCP-5, is a small cytokine belonging to the CC chemokine family. It is a structural and functional homologue of human MCP-1. CCL12 is found predominantly in lymph nodes and thymus under normal conditions, and its expression can be markedly induced in activated macrophages both in vitro and in vivo. CCL12 is involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
参考文献:
1. M N Sarafi. et al. (1997) J Exp Med.185(1):99-109. 2. D.A. Luster. et al. (1998) J Exp Med. 338 (1998), 436-445. 3. G Q Jia. et al. (1996) J Exp Med. 184(5):1939-51.

