Recombinant Mouse ANGPTL4 protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2770

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Synonyms

425O18-1, Angiopoietin-like protein 4, Angiopoietin-related protein 4, ANGPTL4 C-terminal chain, ANGPTL4 N-terminal chain



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Mouse ANGPTL4 protein Arg168-Ser410 (Accession# Q9Z1P8) with a rabbit IgG Fc tag at the C-terminus.
基因ID 57875
蛋白编号 Q9Z1P8
预测分子量 53.4 kDa
SDS-PAGE 57-70 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in 20 mM PB, 150 mM NaCl, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

ANGPTL4 is highly expressed in ATs and liver in humans and mice and to a lesser extent in heart, muscles and other tissues. Expression of ANGPTL4 is regulated by nutritional and metabolic states. For example, ANGPTL4 is induced by fasting and hypoxia in a tissue dependent manner. Its expression is under the regulation of several transcription factors including PPARs, glucocorticoid receptors, hypoxia-inducible factor 1-alpha (HIF1α) and others.

参考文献:

1. Yoon JC et al. (2000). Mol Cell Biol 20 (14), 5343–9. 2. Kersten S et al. (2000). J Biol Chem 275 (37), 28488–93. 3. Belanger AJ et al. (2002). J Mol Cell Cardiol 34 (7), 765–74. 4. Koliwad SK et al. (2009). J Biol Chem 284 (38), 25593–601.

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