Lin28A-specific Monoclonal antibody
Lin28A-specific Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human
Applications
ELISA
Conjugate
Unconjugated
CloneNo.
4H8C1
验证数据展示
产品信息
60147-1-Ig targets Lin28A-specific in ELISA applications and shows reactivity with human samples.
| Tested Applications | ELISA |
| Tested Reactivity | human |
| Immunogen | peptide 种属同源性预测 |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | lin-28 homolog (C. elegans) |
| Synonyms | |
| Calculated Molecular Weight | 23 kDa |
| Observed Molecular Weight | 28 kDa |
| GenBank Accession Number | NM_024674 |
| Gene Symbol | LIN28 |
| Gene ID (NCBI) | 79727 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Caprylic Acid/Ammonium Sulfate Precipitation |
| UNIPROT ID | Q9H9Z2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
LIN28 is one of the four key human factors (OCT4, SOX2, NANOG and LIN28) used to reprogram human fibroblasts to an embryonic stem (ES) cell-like state known as the induced pluripotent stem (Ips) cell. Lin28 is a marker of undifferentiated human embryonic stem cells and a cytoplasmic Mrna-binding protein that binds to and enhances the translation of the IGF2 Mrna. LIN28 has also been shown to bind to the let-7 pre-miRNA and block production of the mature let-7 microRNA in mouse embryonic stem cells. This antibody is a mouse monoclonal antibody raised against a peptide mapping within human LIN28. This antibody recognize Lin28A specifically.