IHCeasy WFS1 Ready-To-Use IHC Kit0 Publications

WFS1 Ready-to-use reagent kit for IHC. | Catalog number: KHC0048

规格

单价

50T

¥3200

50T (With Slide)

¥3400

Product Information


Product name:
IHCeasy WFS1 Ready-To-Use IHC Kit

Sample type:
FFPE tissue

Assay type:
Immunohistochemistry

Primary antibody type:
Rabbit Polyclonal

Secondary antibody type:
Polymer-HRP-Goat anti-Rabbit

Reactivity:
Human, rat, mouse

Description:
KHC0048 is a ready-to-use IHC kit for staining of WFS1. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.

Properties


Storage Instructions:
All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.

Synonyms:
WFRS, WFS, WFS1, Wolfram syndrome 1 (wolframin), WOLFRAMIN

Kit components:
ComponentSizeConcentration
Antigen Retrieval Buffer100 mL50×
Washing Buffer100 mL ×220×
Blocking Buffer5 mLRTU
Primary Antibody5 mLRTU
Secondary Antibody5 mLRTU
Chromogen Component A0.2 mLRTU
Chromogen Component B4 mLRTU
Signal Enhancer5 mLRTU
Counter Staining Reagent5 mLRTU
Mounting Media5 mLRTU
Datasheet1 Copy
Manual1 Copy
Control slide (optional)1 slide
Background

Wolfram syndrome protein (WFS1), also called wolframin, is a transmembrane protein, which is located primarily in the endoplasmic reticulum and its expression is induced in response to ER stress, partially through transcriptional activation. ER localization suggests that WFS1 protein has physiological functions in membrane trafficking, secretion, processing and/or regulation of ER calcium homeostasis. It is ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations of the WFS1 gene are responsible for two hereditary diseases, autosomal recessive Wolfram syndrome and autosomal dominant low frequency sensorineural hearing loss.


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