IHCeasy PAX8 Ready-To-Use IHC Kit0 Publications

PAX8 Ready-to-use reagent kit for IHC. | Catalog number: KHC0038

规格

单价

50T

¥3200

50T (With Slide)

¥3400

Product Information


Product name:
IHCeasy PAX8 Ready-To-Use IHC Kit

Sample type:
FFPE tissue

Assay type:
Immunohistochemistry

Primary antibody type:
Mouse Monoclonal

Secondary antibody type:
Polymer-HRP-Goat anti-Mouse

Reactivity:
Human, rat, mouse

Description:
KHC0038 is a ready-to-use IHC kit for staining of PAX8. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.

Properties


Storage Instructions:
All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.

Synonyms:
paired box 8, Paired box protein Pax 8, PAX8

Kit components:
ComponentSizeConcentration
Antigen Retrieval Buffer100 mL50×
Washing Buffer100 mL ×220×
Blocking Buffer5 mLRTU
Primary Antibody5 mLRTU
Secondary Antibody5 mLRTU
Chromogen Component A0.2 mLRTU
Chromogen Component B4 mLRTU
Signal Enhancer5 mLRTU
Counter Staining Reagent5 mLRTU
Mounting Media5 mLRTU
Datasheet1 Copy
Manual1 Copy
Control slide (optional)1 slide
Background

PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. It is expressed during organogenesis of the thyroid gland, kidney and Mullerian system. It is thought to regulate the expression of Wilms tumor suppressor (WT1) gene and mutations in PAX8 have been associated with Wilms tumor cells, thyroid and ovarian carcinomas. PAX8 is a useful marker in distinguishing ovarian carcinomas from mammary carcinomas (PMID: 18724243). PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas.


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