IHCeasy MAdCAM1 Ready-To-Use IHC Kit0 Publications

MAdCAM1 Ready-to-use reagent kit for IHC. | Catalog number: KHC0025

规格

单价

50T

¥3200

50T (With Slide)

¥3400

Product Information


Product name:
IHCeasy MAdCAM1 Ready-To-Use IHC Kit

Sample type:
FFPE tissue

Assay type:
Immunohistochemistry

Primary antibody type:
Mouse Monoclonal

Secondary antibody type:
Polymer-HRP-Goat anti-Mouse

Reactivity:
Human

Description:
KHC0025 is a ready-to-use IHC kit for staining of MAdCAM1. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.

Properties


Storage Instructions:
All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.

Synonyms:
hMAdCAM 1, MACAM1, MAdCAM 1, MAdCAM1

Kit components:
ComponentSizeConcentration
Antigen Retrieval Buffer100 mL50×
Washing Buffer100 mL ×220×
Blocking Buffer5 mLRTU
Primary Antibody5 mLRTU
Secondary Antibody5 mLRTU
Chromogen Component A0.2 mLRTU
Chromogen Component B4 mLRTU
Signal Enhancer5 mLRTU
Counter Staining Reagent5 mLRTU
Mounting Media5 mLRTU
Datasheet1 Copy
Manual1 Copy
Control slide (optional)1 slide
Background

Lymphocyte recirculation through different organs is thought to be regulated by adhesion molecules ("homing receptors") recognizing tissue-specific vascular addressins on endothelium (PMID: 7511642). The mucosal vascular addressin, MAdCAM1, is an immunoglobulin superfamily adhesion receptor for lymphocytes that is expressed by mucosal venules and helps direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria (PMID: 7687523). MAdCAM1 can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes.


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