验证数据展示
产品信息
| Product name | Human t-Plasminogen activator Antibody Pair Set |
| Tests | 10×96 well plate |
| Assay type | Sandwich |
| Range | 15.6 - 1000 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 5327 |
| Specificity | Please see the product datasheet |
| Entrez Gene ID | 5327(P00750) |
| Alternate Names | Alteplase, DKFZp686I03148, plasminogen activator, tissue, PLAT, Reteplase, T PA, t plasminogen activator, TPA |
背景信息
Plasminogen activator, tissue (PLAT, synonyms: TPA, T-PA) is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein (33 kDa and 32 kDa). PLAT enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. tPA has 4 isoforms produced by alternative splicing with the MW of 63 kDa, 33 kDa, 57 kDa and 44 kDa.
产品特性
- Optimization: The use of matched antibody pairs that have undergone rigorous screening and validation can significantly reduce the time required for development.
- Flexible Packaging: The availability of multiple specifications allows for the detection needs of various sample quantities to be met.
- Economic: This product offers cost-effective solutions for researchers who want to save on their budget while exploring unique sample detection systems in their assays.
- Natural Sample Testing: The product has undergone thorough testing using natural samples.
运输与储存
| Shipping | The product is shipped at 2-8℃. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20℃. Do not use past expiration date. |
