Recombinant Human VEGFD protein (Myc Tag, His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
Myc Tag, His Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 | Not tested |
来源 | HEK293-derived Human VEGFD protein Phe93-Ser201 (Accession# O43915) with a Myc tag and a His tag at the C-terminus. |
基因ID | 2277 |
蛋白编号 | O43915 |
预测分子量 | 17.2 kDa |
SDS-PAGE | 21-31 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Vascular endothelial growth factor-D (VEGFD) is a secreted glycoprotein that can activate VEGF receptors on the endothelium, is a mitogen for endothelial cells and promotes the growth and remodeling of blood vessels and lymphatic vessels. VEGFD undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. VEGFD has been established to be over-expressed in both tumor tissues and patients' serum samples in several types of human cancer.
参考文献:
1. S A Stacker. et al. (2001) Nat Med. 7(2):186-91. 2. M G Achen. et al. (1998) Proc Natl Acad Sci U S A. 20;95(2):548-53. 3. Natalia Davydova. et al. (2016) J Biol Chem. 291(53):27265-27278. 4. Y Yamada. et al. (1997) Genomics. 42(3):483-8.