Recombinant Human Siglec-8 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human Siglec-8 protein Met17-Arg354 (Accession# Q9NYZ4-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 27181 |
| 蛋白编号 | Q9NYZ4-1 |
| 预测分子量 | 63.0 kDa |
| SDS-PAGE | 65-80 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Siglec-8 is a 431-amino acid protein composed of 3 Ig domains with a 358-amino acid extracellular domain and a 47-amino acid tail. Siglec-8 is a member of the CD33-like subgroup of SIGLECs and is expressed specifically in blood cells namely basophil, mast cells, and eosinophils.
参考文献:
1. H Floyd, et al. (2000) J Biol Chem. 275(2):861-6. 2. K K Kikly, et al. (2000) J Allergy Clin Immunol. 105(6 Pt 1):1093-100.
