Recombinant Human CD45 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human CD45 protein Gln26-Lys577 (Accession# P08575-3) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 5788 |
| 蛋白编号 | P08575-3 |
| 预测分子量 | 87.1 kDa |
| SDS-PAGE | 110-200 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets. CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling.
参考文献:
1. F W Shen, et al. (1986) Immunogenetics. 24(3):146-9. 2. J G Altin, et al. (1997) Review Immunol Cell Biol. 75(5):430-45. 3. Nicholas D Huntington, et al. (2006) Nat Immunol. 7(2):190-8. 4. Salema Jafri, et al. (2017) Sci Rep. 7(1):3495.
