Recombinant Human PSCA protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human PSCA protein Leu12-Ser86 (Accession# O43653) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 8000 |
| 蛋白编号 | O43653 |
| 预测分子量 | 34.5 kDa |
| SDS-PAGE | 38-55 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Prostate stem cell antigen (PSCA), composed of 123 amino acid residues, is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein belonging to the Thy-1/Ly-6 family. It is highly expressed in normal prostate and further up-regulated in prostate cancer, as well as non-prostatic malignancies including gastric cancer. PSCA plays a critical role in cell adhesion, proliferation, and survival.
参考文献:
1. R E Reiter, et al. (1998) Proc Natl Acad Sci U S A. 95(4):1735-40. 2. Z Gu, et al. (2000) Oncogene. 19(10):1288-96. 3. Hiromi Sakamoto, et al. (2008) Nat Genet. 40(6):730-40.
