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Recombinant Human PRRG1 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg4097

Print datasheet

Synonyms

PRGP1, Proline-rich gamma-carboxyglutamic acid protein 1, Proline-rich Gla protein 1, TMG1, Transmembrane gamma-carboxyglutamic acid protein 1



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Human PRRG1 protein Ala21-Leu83 (Accession# O14668-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 5638
蛋白编号 O14668-1
预测分子量 33.9 kDa
SDS-PAGE 36-45 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

PRRG1, or proline-rich and Gla domain 1, is a protein-coding gene in humans. It encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein features a Gla domain at the N-terminus, which is essential for the post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus of the protein is proline-rich and contains PPXY and PXXP motifs, which are found in various signaling and cytoskeletal proteins.

参考文献:

1.Kulman JD. et al. (1997) Proc Natl Acad Sci U S A. 94(17):9058-62.

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