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Recombinant Human OXT protein (mFc Tag)(HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

mFc Tag

生物活性

未测试

Cat no : Eg2238

Print datasheet

Synonyms

Neurophysin 1, Ocytocin Neurophysin 1, Oxytocin, Oxytocin neurophysin 1, Oxytocin-neurophysin 1

验证数据展示

  • Purity of Recombinant Human OXT was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human OXT was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human OXT was greater than 90% as determined by SEC-HPLC.

    The purity of Human OXT was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human OXT protein Ala32-Arg125 (Accession# P01178) with a mouse IgG Fc tag at the N-terminus.
基因ID 5020
蛋白编号 P01178
预测分子量 37.3 kDa
SDS-PAGE 33-48 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Oxytocin (OXT), a nine-amino-acid peptide produced in the hypothalamus and released by the posterior pituitary, is well-known for its actions in parturition, lactation, and social behavior. Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland and acts by binding to oxytocin receptor (OXTR).

参考文献:

1. Erwei Li , et al. (2024) Nature. 625(7993):175-180.
2. Sébastien Dutertre , et al. (2008) J Biol Chem. 283(11):7100-8.
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