Recombinant Human NRG2 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human NRG2 protein Cys112-Lys404 (Accession# O14511-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 9542 |
| 蛋白编号 | O14511-1 |
| 预测分子量 | 58.9 kDa |
| SDS-PAGE | 65-85 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
NRG2 is a novel member of the neuregulin family of growth and differentiation factors. By interacting with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial and other cell types. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate different biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is close to the Charcot-Marie-Tooth demyelinating disease locus, but does not cause the disease.
参考文献:
1.Yan L. et al. (2018) Mol Psychiatry. 23(5):1233-1243. 2.Falls DL. (2003) Exp Cell Res. 284(1):14-30. 3.Zhao WJ. et al. (2021) Folia Neuropathol. 59(2):189-197. 4.Czarnek M. et al. (2020) Mol Neurobiol. 57(4):1799-1813.
