Recombinant Human NKG2A protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human NKG2A protein Pro94-Leu233 (Accession# P26715-1) with a rabbit IgG Fc tag at the N-terminus. |
| 基因ID | 3821 |
| 蛋白编号 | P26715-1 |
| 预测分子量 | 43.2 kDa |
| SDS-PAGE | 50-68 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
NKG2A, also known as CD159A, is a single-pass type II membrane protein with extracellular C-type lectin domain. It belongs to the natural killer cell lectin-like receptor family, which is a group of transmembrane proteins preferentially expressed in NK cells. NKG2A can form a heterodimer with CD94. The NKG2A/CD94 complex is an inhibitory receptor that recognizes HLA-E and is expressed by NK cells and a subset of T cells.
参考文献:
1. Chao Zhang. et al. (2019). Nature Communications. volume 10, Article number: 1507. 2. Brett K. Kaiser. et al. (2008). Proc Natl Acad Sci U S A.105(18):6696-701.
