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Recombinant Human NBL1 protein (rFc Tag)(HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg2940

Print datasheet

Synonyms

D1S1733E, DAN, DAND1, NB, Neuroblastoma suppressor of tumorigenicity 1

验证数据展示

  • Purity of Recombinant Human NBL1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human NBL1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human NBL1 was greater than 90% as determined by SEC-HPLC.

    The purity of Human NBL1 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human NBL1 protein Ala17-Asp181 (Accession# P41271-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 4681
蛋白编号 P41271-1
预测分子量 43.7 kDa
SDS-PAGE 45-55 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

NBL1 (neuroblastoma suppression of tumorigenicity 1), also named as DAN, is the founding member of the DAN subfamily. It was originally identified as a putative tumor suppressor gene in a transformed fibroblast rat model, whereby it was significantly down-regulated in v-src-transformed rat fibroblasts. The MW of this protein is 19 kDa, and this antibody specially recognises the 19 kDa protein.

参考文献:

1. Tsai CH. et al.  (2023) Biomolecules. 13(11):1570. 
2. Ladenstein R. et al. (2018) Lancet Oncol. 19(12):1617-1629. 
3. Lu L. et al. (2022) Oncogenesis. 11(1):21. 
4. Du J. et al. (2023) Thorac Cancer. 14(30):3032-3041. 
5. Wang A. et al. (2022) Parasitol Res. 121(5):1369-1378.
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