Recombinant Human MAG protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 |
Not tested |
来源 | HEK293-derived Human MAG protein Gly20-Pro516 (Accession# P20916-1) with a rabbit IgG Fc tag at the C-terminus. |
基因ID | 4099 |
蛋白编号 | P20916-1 |
预测分子量 | 80.7 kDa |
SDS-PAGE | 90-120 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
MAG (myelin associated glycoprotein) is a 100-kDa transmembrane glycoprotein that is a member of the SIGLEC family of proteins. MAG is localized in periaxonal Schwann cell and oligodendroglial membranes of myelin sheaths where it functions in glia-axon interactions. It is a functional ligand for the Nogo-66 receptor. MAG is a cell adhesion molecule for postnatal neural development and is thought to be involved in the process of myelination.
参考文献:
1. Quarles RH. (2007) J Neurochem. 100(6):1431-48. 2. Liu BP. et al. (2002) Science. 297(5584):1190-3.