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Recombinant Human MAG protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2975

Print datasheet

Synonyms

MAG, GMA, myelin associated glycoprotein, S MAG, SIGLEC 4A

验证数据展示

  • Purity of Recombinant Human MAG was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human MAG was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human MAG protein Gly20-Pro516 (Accession# P20916-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 4099
蛋白编号 P20916-1
预测分子量 80.7 kDa
SDS-PAGE 90-120 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

MAG (myelin associated glycoprotein) is a 100-kDa transmembrane glycoprotein that is a member of the SIGLEC family of proteins. MAG is localized in periaxonal Schwann cell and oligodendroglial membranes of myelin sheaths where it functions in glia-axon interactions. It is a functional ligand for the Nogo-66 receptor. MAG is a cell adhesion molecule for postnatal neural development and is thought to be involved in the process of myelination.

参考文献:

1. Quarles RH. (2007) J Neurochem. 100(6):1431-48. 
2. Liu BP. et al. (2002) Science. 297(5584):1190-3.