Recombinant Human LHB protein (mFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
mFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human LHB protein Ser21-Leu141 (Accession# P01229) with a mouse IgG Fc tag at the C-terminus. |
| 基因ID | 3972 |
| 蛋白编号 | P01229 |
| 预测分子量 | 39.8 kDa |
| SDS-PAGE | 43-48 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Lutropin Subunit Beta, also known as LHB, is a member of the glycoprotein hormone beta chain family. It encodes the beta subunit of luteinizing hormone (LH), expressed in the pituitary gland, and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. LHB is synthesized and secreted by the gonadotropes within the anterior pituitary gland. Mutations in the LHB gene are associated with hypogonadism, characterized by infertility and pseudohermaphroditism.
参考文献:
1.Keutmann HT. et al. (1987). Proc Natl Acad Sci U S A. 84(7):2038-2042. 2.Jablonka-Shariff A. et al. (2008). J Biol Chem. 283(17):11485-11492. Lofrano-Porto A. et al. (2007). N Engl J Med. 357(9):897-904.
