Recombinant Human IL-1F6/IL-36 Alpha protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human IL-1F6 protein Lys6-Phe158 (Accession# Q9UHA7) with a rabbit IgG Fc tag at the N-terminus. |
| 基因ID | 27179 |
| 蛋白编号 | Q9UHA7 |
| 预测分子量 | 44.3 kDa |
| SDS-PAGE | 49-60 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
IL1F6, also known as IL36A, is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. IL1F6 functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.
参考文献:
1. Smith DE, et al. (2000). J Biol Chem. 275(2):1169-75. 2. Johnston A, et al. (2011). J Immunol. 186(4):2613-22.
