验证数据展示
产品信息
Product name | Human CXCL8/IL-8 Antibody Pair Set |
Tests | 10×96 well plate |
Assay type | Sandwich |
Range | 3.13-200 pg/mL |
Reactivity | Human |
Tested applications | Sandwich ELISA |
Gene ID (NCBI) | 3576 |
Specificity | Please see the product datasheet |
Entrez Gene ID | 3576(P10145) |
Alternate Names | CXCL8, IL 8, IL8, IL-8, interleukin 8 |
背景信息
Interleukin 8 (IL-8), also known as CXCL8, which is a member of the CXC chemokine family. This chemokine is secreted by a variety of cell types including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli. IL-8 has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL-8 also induces phagocytosis once they have arrived. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 is also known to be a potent promoter of angiogenesis. IL-8 has been associated with tumor angiogenesis, metastasis, and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression.
产品特性
- Optimization: The use of matched antibody pairs that have undergone rigorous screening and validation can significantly reduce the time required for development.
- Flexible Packaging: The availability of multiple specifications allows for the detection needs of various sample quantities to be met.
- Economic: This product offers cost-effective solutions for researchers who want to save on their budget while exploring unique sample detection systems in their assays.
- Natural Sample Testing: The product has undergone thorough testing using natural samples.
运输与储存
Shipping | The product is shipped at 2-8℃. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Store the unopened product at -20℃. Do not use past expiration date. |