Recombinant Human ICAM2/CD102 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 | Not tested |
来源 | HEK293-derived Human ICAM2 protein Lys25-Gln223 (Accession# P13598) with a rabbit IgG Fc tag at the C-terminus. |
基因ID | 3384 |
蛋白编号 | P13598 |
预测分子量 | 48.4 kDa |
SDS-PAGE | 60-80 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
ICAM2 is a cell adhesion protein having important roles in cell migration, especially during inflammation when leukocytes cross the endothelium. Initially described as a receptor for lymphocyte function-associated antigen-1 (LFA1), ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
参考文献:
1. J Xie, et al. (1995) J Immunol. Oct 1;155(7):3619-28. 2. B Ybarrondo, C C Shih. (2001) J Biol Regul Homeost Agents. Apr-Jun;15(2):188-9. 3. D L Simmons. (1995) Cancer Surv. 24:141-55.